1 - . studies on the inhibition of angiogenic properties by monoclonal antibody against integrin endothelial cell adhesion and migration are important processes during angiogenesis . the capacity of endothelial cells to recognize and migrate in response to the extracellular matrix ( ecm ) depends on one or more members of the integrin family of cell adhesion receptors 血管新生的过程依赖于参与血管生成的细胞因子和细胞粘附的协同作用,整合素( integrin )是一组细胞表面受体,介导细胞-细胞间、细胞-基质间的相互作用,对内皮细胞的粘附、迁移、增殖起重要作用。